Patents, publications, and FDA-cleared technologies

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Selected U.S. patents representing key technology platforms

Demineralized Bone Matrix (DBM) & Osteoinductive Technologies

U.S. 9,415,136 — Osteoinductive Demineralized Cancellous Bone

U.S. 8,202,539 — Bone Matrix Compositions and Methods

Bone Morphogenetic Protein (BMP) Delivery & Regulation

U.S. 9,333,237 — BMP Binding Peptide

U.S. 9,610,320 — Surgical Application of BBP

Tissue Processing & Viral Inactivation

U.S. 8,642,061 — Viral Inactivation of Tissue Grafts

Bone Nanoarchitecture & Surface Engineering

U.S. 10,220,115 — Bone Matrix Nano-Textured Surfaces

Surgical Grafts & Implant Technologies

U.S. 9,717,822 — Surgical Graft / Delivery System

Key contributions to four FDA-cleared technologies spanning tissue-based products, spinal implants, additive manufacturing, and synthetic bone graft substitutes

K082615Grafton II Enhanced DBM (MagniFuse®)

Conceived the product concept in response to a strategic initiative to develop procedure-specific bone grafts beyond general-use DBM products. Led scientific development and commercialization of the enhanced demineralized bone matrix (DBM) platform, including product development, biological characterization, and support of FDA regulatory clearance.

K121316Alpine Adjustable Implant System

Supported engineering efforts by identifying titanium plasma spray (TPS) as the preferred surface roughening technology following characterization of osteoblast responses to multiple surface treatments in tissue culture.

K171495Zyston Strut 3D-Printed Titanium Cage

Supported engineering efforts by investigating prototype failures using scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS). Identified fracture nucleation associated with print media contamination and recommended alternative titanium print media that resolved the issue.

K203218CaP Sphere Pellet Pack — Second-Generation Synthetic Bone Void Filler

Developed the formulation, final product configuration, and delivery system. Supported manufacturing scale-up and established the product's technical market positioning.