Founder Accomplishments
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Selected U.S. Patents Representing Key Technology Platforms

Technology Platform Representative Patents
Demineralized Bone Matrix (DBM) & Osteoinductive Technologies
US 9,415,136 – Osteoinductive Demineralized Cancellous Bone
US 8,202,539 – Bone Matrix Compositions and Methods
Bone Morphogenetic Protein (BMP) Delivery & Regulation
US 9,333,237 – BMP Binding Peptide
US 9,610,320 – Surgical Application of BBP
Tissue Processing & Viral Inactivation
US 8,642,061 – Viral Inactivation of Tissue Grafts
Bone Nanoarchitecture & Surface Engineering
US 10,220,115 – Bone Matrix Nano-Textured Surfaces
Surgical Grafts & Implant Technologies
US 9,717,822 – Surgical Graft / Delivery System

Key contributions to four FDA-cleared technologies spanning tissue-based products, spinal implants, additive manufacturing, and synthetic bone graft substitutes

FDA 510(k) Technology Representative Contributions
K082615 Grafton II Enhanced DBM (MagniFuse®) Conceived the product concept in response to a strategic initiative to develop procedure-specific bone grafts beyond general-use DBM products. Led scientific development and commercialization of the enhanced demineralized bone matrix (DBM) platform, including product development, biological characterization, and support of FDA regulatory clearance.
K121316 Alpine Adjustable Implant System Supported engineering efforts by identifying titanium plasma spray (TPS) as the preferred surface roughening technology following characterization of osteoblast responses to multiple surface treatments in tissue culture.
K171495 Zyston Strut 3D-Printed Titanium Cage Supported engineering efforts by investigating prototype failures using scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS). Identified fracture nucleation associated with print media contamination and recommended alternative titanium print media that resolved the issue.
K203218 CaP Sphere Pellet Pack – Second-Generation Synthetic Bone Void Filler Developed the formulation, final product configuration, and delivery system. Supported manufacturing scale-up and established the product's technical market positioning.